Class: NSAID (Selective COX-2 inhibitor) + Muscle relaxant / analgesic combination

Manufacturer:

Dosage Form: Capsules

Similar Brands:

Uses:

• Musculoskeletal pain

• Muscle spasm

• Back pain

• Joint pain and inflammation

• Arthritis with muscle spasm

• Sprains and strains

Dosage:

Adults:

Usually 1 capsule once or twice daily after food, or as directed by a doctor.

Side Effects:

Common:

• Drowsiness

• Dizziness

• Stomach upset

• Headache

Less common:

• Nausea

• Diarrhea

• Fatigue

Rare:

• Allergic reactions

• Liver dysfunction (due to chlorzoxazone)

Warnings & Precautions:

• Use cautiously in patients with liver disease.

• May cause drowsiness, avoid driving or operating machinery.

• Use with caution in cardiovascular disease.

• Avoid alcohol, as it increases liver toxicity risk.

Pregnancy & Lactation:

• Not recommended during pregnancy.

• Contraindicated in the third trimester due to risk of premature closure of the fetal ductus arteriosus and complications during labour.

• Use with caution during breastfeeding and only if prescribed by a doctor

Drug Interactions:

• Anticoagulants (e.g., warfarin) – Increased risk of bleeding due to celecoxib.

• Other NSAIDs or corticosteroids – Increased risk of gastrointestinal ulcer or bleeding.

• ACE inhibitors / ARBs and diuretics – May reduce antihypertensive effect and increase risk of kidney impairment.

• Alcohol – Increased risk of liver toxicity and CNS depression (especially due to chlorzoxazone).

• CNS depressants (sedatives, antihistamines) – May increase drowsiness and dizziness.

• Lithium – Celecoxib may increase lithium levels in the blood.

Contraindications:

• Hypersensitivity to celecoxib, chlorzoxazone, or NSAIDs

• Peptic ulcer or GI bleeding

• Severe liver impairment

• Late pregnancy (third trimester)

Price: Ksh 800/-

Notes:

Pack Size: 10s