Guaifenesin 100 mg, Diphenhydramine HCl 12.5 mg
Class: Expectorant + Antihistamine cough syrup
Manufacturer:
Dosage Form: Oral syrup
Similar Brands:
Uses:
Symptomatic relief of productive coughs and chest congestion, including:
- Wet/chesty cough with thick mucus/phlegm (helps loosen and make it easier to cough up).
- Cough associated with common cold, flu, bronchitis, or upper respiratory tract irritation.
- Congestion, minor throat irritation, or allergy-related chest symptoms.
Not for dry/non-productive coughs (may thicken secretions further) or persistent coughs from smoking, asthma, or chronic conditions—consult doctor for those. Adjunctive for symptom relief; not curative for infections (antibiotics if bacterial).
Dosage:
Take orally, every 4–6 hours as needed (do not exceed 4 doses/24 hours; shake bottle; use measuring device).
Adults and children ≥12 years: 10 mL (2 teaspoonfuls) every 4 hours or 20 mL (4 teaspoonfuls) every 6–8 hours (max 60–80 mL/day).
Children 6–12 years (if advised): 5 mL (1 teaspoonful) every 6–8 hours.
Children under 6/12 years: Not recommended (many labels advise against use in <12 years due to sedation/respiratory risks).
Duration: Short-term (e.g., 3–7 days); seek medical advice if no improvement, symptoms persist >1 week, or worsen (fever, shortness of breath, wheezing).
Side Effects:
Common (mild/transient): Drowsiness/sedation (from diphenhydramine), dizziness, dry mouth/nose/throat, nausea, constipation, headache.
Less common: Restlessness/excitation (paradoxical in children), blurred vision, gastrointestinal upset.
Serious (rare, seek immediate care): Severe allergic reactions (rash, swelling, breathing difficulty), excessive sedation/confusion, respiratory depression (high doses), or paradoxical worsening of cough.
Warnings & Precautions:
Causes drowsiness—avoid driving/machinery, alcohol, sedatives (potentiates CNS depression).
Use caution in asthma/COPD (thickened secretions risk), glaucoma, prostate issues, urinary retention, or elderly (anticholinergic effects).
Not for children under 12 years without doctor/pharmacist guidance.
Monitor for persistent cough, high fever, wheezing, or bloody sputum—seek doctor (may indicate infection).
Contains excipients (e.g., sweeteners—caution in diabetes; preservatives like sodium benzoate).
Discard opened bottle after 4 weeks (contamination risk).
Use caution in asthma/COPD (thickened secretions risk), glaucoma, prostate issues, urinary retention, or elderly (anticholinergic effects).
Not for children under 12 years without doctor/pharmacist guidance.
Monitor for persistent cough, high fever, wheezing, or bloody sputum—seek doctor (may indicate infection).
Contains excipients (e.g., sweeteners—caution in diabetes; preservatives like sodium benzoate).
Discard opened bottle after 4 weeks (contamination risk).
Pregnancy & Lactation:
Pregnancy: Not recommended (limited data; safety not established—consult doctor).
Lactation: Not recommended (diphenhydramine passes into milk; risk of infant sedation/respiratory effects).
Drug Interactions:
CNS depressants (alcohol, sedatives, opioids, hypnotics): Enhanced drowsiness/respiratory depression.
Anticholinergics: Additive effects (dry mouth, constipation).
MAO inhibitors: Potential interactions (avoid).
Anticholinergics: Additive effects (dry mouth, constipation).
MAO inhibitors: Potential interactions (avoid).
Contraindications:
Hypersensitivity to guaifenesin, diphenhydramine, or excipients.
Severe respiratory depression or acute asthma exacerbation.
Children under 12 years (per many labels).
Concomitant MAO inhibitors (or within 14 days).
Severe respiratory depression or acute asthma exacerbation.
Children under 12 years (per many labels).
Concomitant MAO inhibitors (or within 14 days).
Price: Ksh 898/-
Notes:
100 mL bottle