Funbact – A Cream

Class: Anti-inflammatory, antibacterial, anti-fungal

Manufacturer: Bliss GVS Pharma Ltd

Dosage Form: Cream

Similar Brands:

Uses:

Funbact – A cream provides a comprehensive treatment for various inflammatory dermatological disorders superadded with bacterial or superficial fungal infections of the skin. Betamethasone dipropionate is one of the most potent topical corticosteroid available and rapidly controls the symptoms such as itching , redness and scaling.

Many times the inflammatory skin disorders which respond to topical corticosteroids are superadded with bacterial and / or fungal infection of the skin. In these conditions, treatment with anti-inflammatory agents alone is not sufficient and a proper antibiotic has to be added in the regimen. Clotrimazole is a broad spectrum synthetic antifungal agent which has fungicidal action against all the fungi responsible for superficial fungal infections of the skin. Neomycin sulphate is a broad spectrum antibacterial.

Hence, funbact – a cream effectively controls inflammatory disorders superadded with bacterial and / or fungal infection of the skin.

Dosage:

Funbact-A cream  should be thinly and evenly applied to the affected area two to three times a day with gently rub.

Side Effects:

There are reports of local skin irritation, burning, pruritus, pigmentation changes, allergic contact dermatitis and hypertrichosis with topical steroids. Funbact a cream preparation is usually well tolerated, but if signs of hypersensitivity appear, application should be stopped immediately. Side effects includes some of the immune system disorders: allergic reaction (syncope, hypotension, dyspnea, urticaria) skin and subcutaneous tissue disorders: blisters, discomfort/pain, oedema, irritation, peeling/exfoliation, pruritus, rash, stinging/burning.

Warnings & Precautions:

Long term continuous topical therapy should be avoided where possible, particularly in infants and children, as adrenal suppression, with or without clinical features of cushing’s syndrome, can occur even without occulusion. In this situation, topical steroids should be discontinued gradually under medical supervision because of the risk of adrenal insufficiency. If the infection persists, synstemic chemotherapy is required. Withdraw topical corticosteroid if there is a spread of infection. Bacterial infection is encouraged by the warm, moist conditions induced by occlusive dressings, and the skin should be cleansed before a fresh dressing is applied. Extended or recurrent application may increase the risk of contact sensitization. Extension of infection may occur due to the masking effect of the steroid. Following significant systemic absorption, aminoglycosides such as neomycin can cause irreversible ototoxicity; and neomycin has nephrotoxic potential. In renal impairment the plasma clearance of neomycin is reduced.

Pregnancy & Lactation:

Pregnancy

Clotrimazole can be used during pregnancy, but only under the supervision of a physician. There is little information to demonstrate the possible effect of topically applied neomycin  in pregnancy and lactation. However, neomycin present in maternal blood can cross the placenta and my give rise to a theoretical risk of foetal toxicity. To date, no other relevant epidemiological data is available. There are no adequate and well controlled studies of the teratogenic  potential of topically applied betamethasone dipropionate in pregnant women. Therefore funbacta should be used during pregnancy only if the potential risk benefit justifiesthe potential risk to the foetus.

Breast feeding

It is unknown whether it is excreted in breast milk, so it should be given with caution to lactating mothers.

Drug Interactions:

When used together, this product my cause damage to latex contraceptives. Consequently the effectiveness of such contraceptives may be reduced. Patients should be advised to use alternative precautions for at least 5 days after using the product. Following significant systemic absorption, neomycin sulphate can intensify and prolong the respiratory depressant effects of neuromuscular blocking agents.

Contraindications:

Hypersensitivity to clotrimazole, neomycin sulphate and bethamethasonedipropionate or any of the excipients.

Price: Ksh 180

Notes:

Pack Size: 15gms & 30gms tubes

Funbact – A Cream 15gms is Ksh 100/-

Funbact – A Cream 30gms is Ksh 180/-

Compositititon

Each gm contains;

Clotrimazole USP 1.0%w/w, Betametasonedipropionate 0.05%w/w, Neomycin sulphate USP 0.5%w/w, Preservative – chlorocresol USP NF 0.1% w/w, cream base q.s.

Overdose

Acute over dosage is very unlikely to occur. However, in the case of chronic over dosage or misuse the features of Cushing’s syndrome may appear and in this situation topical steroids should be discontinued gradually under medical supervision. Also, consideration should be given to significant systemic absorption of neomycin sulphate. If this is suspected, use of the product should be stopped and the patient’s general status, hearing ability renal and neuromuscular functions should be monitored. Blood levels of neomycin sulphate should also be determined. Hemodialysis may reduce the serum level of neomycin sulphate. In the event of accidental oral ingestion, gastric lavage is rarely required and should be considered only if a life threatening amount of clotrimazole has been ingested with the preceding hour or if clinical symptoms of overdose become apparent (e.g. dizziness, nausea or vomiting). It should be carried out only if the airway can be protected adequately.

Ref: 13007550