Ascoril Expectorant

Salbutamol 2 mg, Bromhexine Hydrochloride BP 4 mg, Guaifenesin USP 100 mg

Class: Mucolytic + Bronchodilator + Expectorant combination

Manufacturer: Glenmark Pharmaceuticals

Dosage Form: Oral syrup

Similar Brands:

Uses:

  • Productive cough (chest cough with mucus)

  • Acute and chronic bronchitis

  • Bronchial asthma (with mucus)

  • COPD

  • Other respiratory tract infections with thick sputum

Dosage:

Adults: 10 mL three times daily
Children 6–12 years: 5–10 mL three times daily
Children 2–6 years: 5 mL three times daily

(Adjust according to prescriber guidance.)

Side Effects:

Common

  • Tremors

  • Palpitations

  • Nervousness

  • Nausea, vomiting

  • Headache

Less common

  • Muscle cramps

  • Dizziness

  • Skin rash

Serious (rare)

  • Severe allergic reactions

  • Significant tachycardia

Warnings & Precautions:

  • Use cautiously in patients with heart disease or hypertension.

  • Caution in diabetes (salbutamol may affect blood sugar).

  • Avoid overdose — may cause serious heart rhythm disturbances.

  • Not recommended for dry cough (since it is an expectorant).

  • Use carefully in hyperthyroidism.

Pregnancy & Lactation:

  • Use only if clearly prescribed during pregnancy.

  • Consult healthcare provider before use in breastfeeding.

Drug Interactions:

  • Beta-blockers (reduce salbutamol effect)

  • Diuretics (risk of low potassium)

  • Other sympathomimetics

  • MAO inhibitors and tricyclic antidepressants

Contraindications:

  • Hypersensitivity to any component

  • Severe cardiac disorders

  • Tachyarrhythmias

Price: Ksh 292/- (Ascoril Expectorant 100ml), 565/- (Ascoril Expectorant 200ml)

Notes:

Composition (per 5 mL)

  • Salbutamol Sulphate BP 2 mg

  • Bromhexine Hydrochloride BP 4 mg

  • Guaifenesin BP 100 mg

  • Menthol 1 mg

Pharmacological Action

  • Salbutamol – Relaxes bronchial smooth muscle (bronchodilator)

  • Bromhexine – Breaks down thick mucus (mucolytic)

  • Guaifenesin – Loosens and helps expel mucus (expectorant)

  • Menthol – Provides soothing effect