Celecoxib – 200 mg
Class: Selective COX-2 inhibitor (Non-steroidal anti-inflammatory drug – NSAID)
Manufacturer:
Dosage Form: Capsules
Similar Brands:
Uses:
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Osteoarthritis
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Rheumatoid arthritis
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Ankylosing spondylitis
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Acute pain
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Musculoskeletal pain
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Dysmenorrhea (painful menstruation)
Dosage:
Adults:
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Osteoarthritis: 200 mg once daily or 100 mg twice daily
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Rheumatoid arthritis: 100–200 mg twice daily
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Acute pain / dysmenorrhea: 400 mg initially, followed by 200 mg if needed on the first day, then 200 mg twice daily if required
Take with or without food as directed by a doctor.
Side Effects:
Common:
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Stomach pain
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Diarrhea
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Headache
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Indigestion
Less common:
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Dizziness
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Nausea
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Hypertension
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Peripheral edema
Serious (rare):
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Gastrointestinal bleeding
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Cardiovascular events (heart attack or stroke)
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Severe allergic reactions
Warnings & Precautions:
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Use cautiously in patients with cardiovascular disease.
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May increase risk of heart attack or stroke with long-term use.
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Use carefully in kidney or liver impairment.
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Avoid in patients with sulfonamide allergy.
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Use the lowest effective dose for the shortest duration.
Pregnancy & Lactation:
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First and Second Trimester: Use only if clearly needed and prescribed by a doctor.
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Third Trimester: Contraindicated
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Celecoxib may cause premature closure of the fetal ductus arteriosus.
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It may also lead to delayed labour and increased bleeding risk.
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Use in Lactation
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Celecoxib passes into breast milk in small amounts.
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Use with caution during breastfeeding and only on medical advice.
Drug Interactions:
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Anticoagulants (e.g., warfarin) – increased bleeding risk
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ACE inhibitors and diuretics – reduced antihypertensive effect
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Lithium – increased lithium levels
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Other NSAIDs – increased GI toxicity
Contraindications:
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Hypersensitivity to celecoxib or sulfonamides
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History of asthma or allergic reactions to NSAIDs
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Peptic ulcer or gastrointestinal bleeding
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Severe heart failure
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Late pregnancy (third trimester)
Price: Ksh 450/-
Notes:
Pack Size: 10s