Class: Analgesic and antipyretic combination (non-opioid pain reliever with stimulant adjuvant)

Manufacturer: Elys Chemical Industries Ltd, Biodeal Laboratories Ltd

Dosage Form: Oral tablets

Similar Brands:

Uses:

• Relief of mild to moderate pain (e.g. headache, toothache, musculoskeletal pain)

• Fever reduction

• Migraine and tension headaches

• Pain associated with colds or flu

Dosage:

• Adults and children ≥12 years: 1–2 tablets every 4–6 hours as needed.

• Do not exceed the recommended daily dose (follow product label).

• Take with water, preferably after food to reduce stomach irritation.

Side Effects:

• Gastric irritation, heartburn, nausea, or vomiting

• Increased risk of bleeding or bruising (aspirin effect)

• Nervousness, insomnia, palpitations (caffeine)

• Allergic reactions (rash, swelling, breathing difficulty)

• Liver toxicity with excessive paracetamol use

Warnings & Precautions:

• Avoid use with other paracetamol- or aspirin-containing medicines.

• Use cautiously in patients with peptic ulcer disease, bleeding disorders, asthma, liver disease, or kidney impairment.

• Limit caffeine intake from other sources.

• Avoid alcohol while using this medicine.

• Not recommended for children with viral infections due to risk of Reye’s syndrome (aspirin component).

• Prolonged use should be under medical supervision.

Pregnancy & Lactation:

• Avoid during pregnancy, especially in the third trimester (aspirin risk).

• Use only if clearly necessary and advised by a healthcare professional.

• Aspirin and caffeine pass into breast milk; caution in breastfeeding.

Drug Interactions:

• Anticoagulants and antiplatelet drugs (increased bleeding risk)

• NSAIDs and corticosteroids (increased GI irritation)

• Alcohol (increased liver and stomach toxicity)

• Methotrexate, warfarin, and other highly protein-bound drugs

• Stimulants or high caffeine intake (additive CNS effects)

Contraindications:

• Hypersensitivity to paracetamol, aspirin, caffeine, or salicylates

• Active peptic ulcer or gastrointestinal bleeding

• Severe liver or kidney impairment

• Bleeding disorders

• Children and adolescents with viral infections

• Aspirin-induced asthma or salicylate sensitivity

Price: Ksh 200/-

Notes:

Pack Size:100s

February 7, 2025
Medicine Quality Alert: Class II Recall of A.P.C Tablets
Biodeal Laboratories Ltd voluntarily recalled A.P.C Tablets (Paracetamol B.P, Aspirin B.P, Caffeine Anhydrous B.P), batch 1223038 (mfg. 12/2023, exp. 11/2026, pack of 100s) due to out-of-specification weight uniformity. Issued by Pharmacy and Poisons Board (REC/2025/004), affecting all counties at retail/facility level