Apflu Syrup 100ml

Chlorphenamine Maleate BP 0.5 mg Paracetamol BP 120 mg Vitamin C (Ascorbic acid) BP 50 mg (per 5ml)

Class: Antihistamine + analgesic/antipyretic + vitamin supplement (cold and flu combination medicine)

Manufacturer: Ajanta Pharma Limited

Dosage Form: Oral syrup (brown to light brown, mango-flavoured)

Similar Brands:

Uses:

  • Symptomatic relief of common cold and flu

  • Fever and body aches

  • Headache and toothache (Also indicated for the reduction of toothache)

  • Runny or blocked nose

  • Sneezing, itching, watery eyes (allergy symptoms)

  • Sinus congestion

Dosage:

  • 1–2 years: 5 mL four times daily

  • 2–8 years: 10 mL four times daily

  • 8–10 years: 15 mL four times daily

  • 10–12 years: 20 mL four times daily
    Do not exceed recommended dose.

Side Effects:

Chlorphenamine-related

  • Drowsiness, dizziness, sedation

  • Blurred vision

  • Dry mouth, nausea

  • Confusion, irritability (especially in children/elderly)

  • Urinary retention, palpitations (rare)

Paracetamol-related

  • Skin rash or allergic reactions (rare)

  • Liver toxicity in overdose

Vitamin C-related

  • Nausea, stomach cramps

  • Diarrhoea with high doses

  • Headache, flushing

Warnings & Precautions:

  • May cause drowsiness; avoid driving or operating machinery.

  • Avoid alcohol and other sedative medicines.

  • Do not use with other paracetamol-containing products.

  • Use cautiously in liver or kidney impairment.

  • Caution in glaucoma, asthma, epilepsy, prostatic enlargement, cardiovascular disease.

  • May interfere with certain laboratory tests (glucose, uric acid, creatinine).

  • Children and elderly may experience stronger anticholinergic effects.

Pregnancy & Lactation:

  • Use during pregnancy only if clearly necessary and prescribed.

  • Not recommended during breastfeeding unless advised by a doctor (may reduce milk production and pass into breast milk).

Drug Interactions:

  • Sedatives, anxiolytics, alcohol (increased sedation)

  • MAO inhibitors (contraindicated within 14 days)

  • Warfarin and other anticoagulants (bleeding risk with prolonged use)

  • Liver enzyme-inducing drugs (increase paracetamol toxicity risk)

  • Metoclopramide, domperidone, colestyramine (affect paracetamol absorption)

  • Phenytoin (toxicity risk)

  • Iron (vitamin C increases absorption)

  • Aluminium-containing antacids (interaction with vitamin C)

Contraindications:

  • Hypersensitivity to chlorphenamine, paracetamol, vitamin C, or excipients

  • Severe hepatic impairment

  • Use with MAO inhibitors (or within previous 14 days)

  • Hyperoxaluria (vitamin C component)

Price: Ksh 243/-

Notes:

Available in 100 ml Amber Glass bottle in a carton along with pack insert.