Ambroxol/Terbutaline/Guaifenesin
Class: Mucolytic / Expectorant + Bronchodilator cough syrup
Manufacturer: Pharmaken Ltd Kenya
Dosage Form: Syrup
Similar Brands:
Uses:
Symptomatic relief of productive (wet/chesty) cough and respiratory congestion, including:
- Cough with thick/viscid mucus (e.g., from common cold, flu, bronchitis).
- Bronchospasm/constricted airways with mucus buildup.
- Acute/chronic bronchitis, tracheobronchitis, or COPD exacerbations with phlegm.
- Conditions where mucus clearance is difficult (helps thin/loosen mucus for easier expectoration and promotes better breathing).
Not for dry/irritative cough (may worsen); not curative for infections (use antibiotics if bacterial)—adjunctive for symptom relief.
Dosage:
Take orally, with or without food (often after meals to reduce GI upset). Typical (follow label/pharmacist advice; adjust for age/severity):
Adults and children >12 years: 10 mL (2 teaspoonfuls) 3 times daily.
Children 6–12 years: 5–10 mL (1–2 teaspoonfuls) 3 times daily.
Children 2–6 years: 5 mL (1 teaspoonful) 3 times daily (consult doctor/pharmacist).
Duration: Short-term (e.g., 4–5 days); seek medical advice if symptoms persist >4–5 days or worsen (e.g., fever, wheezing). Not for infants <2 years without guidance. Use measuring device for accuracy.
Adults and children >12 years: 10 mL (2 teaspoonfuls) 3 times daily.
Children 6–12 years: 5–10 mL (1–2 teaspoonfuls) 3 times daily.
Children 2–6 years: 5 mL (1 teaspoonful) 3 times daily (consult doctor/pharmacist).
Duration: Short-term (e.g., 4–5 days); seek medical advice if symptoms persist >4–5 days or worsen (e.g., fever, wheezing). Not for infants <2 years without guidance. Use measuring device for accuracy.
Side Effects:
Common (mild, often transient): Nausea, vomiting, abdominal pain/upset, diarrhea, dry mouth/throat, headache, dizziness, tremor (from bronchodilator), increased heart rate, restlessness.
Less common: Skin rash/itching, allergic reactions, taste changes.
Serious (rare, seek immediate care): Severe allergic reactions (rash, swelling, breathing difficulty), bronchospasm worsening, irregular heartbeat, severe GI issues, or signs of hypersensitivity (e.g., anaphylaxis).
Less common: Skin rash/itching, allergic reactions, taste changes.
Serious (rare, seek immediate care): Severe allergic reactions (rash, swelling, breathing difficulty), bronchospasm worsening, irregular heartbeat, severe GI issues, or signs of hypersensitivity (e.g., anaphylaxis).
Warnings & Precautions:
Use caution in asthma (bronchodilator may help but monitor for paradoxic worsening), heart disease (tachycardia risk), diabetes (some formulations affect blood sugar), hyperthyroidism, or glaucoma.
Not for dry cough or if mucus is not present (may hinder clearance).
Seek doctor if persistent cough, high fever, shortness of breath, bloody sputum, or no improvement after 4–5 days.
Contains excipients (e.g., sugars/flavors)—check if diabetic.
Avoid alcohol (may enhance sedation/dizziness).
Not for dry cough or if mucus is not present (may hinder clearance).
Seek doctor if persistent cough, high fever, shortness of breath, bloody sputum, or no improvement after 4–5 days.
Contains excipients (e.g., sugars/flavors)—check if diabetic.
Avoid alcohol (may enhance sedation/dizziness).
Pregnancy & Lactation:
Pregnancy: Limited data; bronchodilators/mucolytics often used if needed but consult doctor (potential risks—avoid unless benefit outweighs).
Lactation: Minimal excretion expected; generally low risk short-term but consult provider (monitor infant for GI effects or restlessness).
Lactation: Minimal excretion expected; generally low risk short-term but consult provider (monitor infant for GI effects or restlessness).
Drug Interactions:
Minimal major for standard use, but:
Beta-blockers (e.g., propranolol): May counteract bronchodilator.
Other sympathomimetics: Additive tachycardia.
MAO inhibitors/antidepressants: Potential interactions.
Beta-blockers (e.g., propranolol): May counteract bronchodilator.
Other sympathomimetics: Additive tachycardia.
MAO inhibitors/antidepressants: Potential interactions.
Contraindications:
Known hypersensitivity to any component (e.g., ambroxol/bromhexine, terbutaline/salbutamol, guaifenesin).
Severe heart conditions or uncontrolled arrhythmias (bronchodilator risk).
Children under 2 years (or per label).
Untreated hyperthyroidism or pheochromocytoma.
Severe heart conditions or uncontrolled arrhythmias (bronchodilator risk).
Children under 2 years (or per label).
Untreated hyperthyroidism or pheochromocytoma.
Price: Ksh 484/-
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