Class: Mucolytic + Bronchodilator + Expectorant combination

Manufacturer: Glenmark Pharmaceuticals

Dosage Form: Oral syrup

Similar Brands:

Uses:

• Productive cough (chest cough with mucus)

• Acute and chronic bronchitis

• Bronchial asthma (with mucus)

• COPD

• Other respiratory tract infections with thick sputum

Dosage:

Adults: 10 mL three times daily
Children 6–12 years: 5–10 mL three times daily
Children 2–6 years: 5 mL three times daily

(Adjust according to prescriber guidance.)

Side Effects:

Common

• Tremors

• Palpitations

• Nervousness

• Nausea, vomiting

• Headache

Less common

• Muscle cramps

• Dizziness

• Skin rash

Serious (rare)

• Severe allergic reactions

• Significant tachycardia

Warnings & Precautions:

• Use cautiously in patients with heart disease or hypertension.

• Caution in diabetes (salbutamol may affect blood sugar).

• Avoid overdose — may cause serious heart rhythm disturbances.

• Not recommended for dry cough (since it is an expectorant).

• Use carefully in hyperthyroidism.

Pregnancy & Lactation:

• Use only if clearly prescribed during pregnancy.

• Consult healthcare provider before use in breastfeeding.

Drug Interactions:

• Beta-blockers (reduce salbutamol effect)

• Diuretics (risk of low potassium)

• Other sympathomimetics

• MAO inhibitors and tricyclic antidepressants

Contraindications:

• Hypersensitivity to any component

• Severe cardiac disorders

• Tachyarrhythmias

Price: Ksh 292/- (Ascoril Expectorant 100ml), 565/- (Ascoril Expectorant 200ml)

Notes:

Composition (per 5 mL)

• Salbutamol Sulphate BP 2 mg

• Bromhexine Hydrochloride BP 4 mg

• Guaifenesin BP 100 mg

• Menthol 1 mg

Pharmacological Action

• Salbutamol – Relaxes bronchial smooth muscle (bronchodilator)

• Bromhexine – Breaks down thick mucus (mucolytic)

• Guaifenesin – Loosens and helps expel mucus (expectorant)

• Menthol – Provides soothing effect