Perindopril Arginine 5mg, Indapamide 1.25 mg
Class: Antihypertensive (ACE inhibitor + Thiazide-like diuretic)
Manufacturer: Servier Laboratories
Dosage Form: Tablet
Similar Brands:
Uses:
- Treatment of hypertension (high blood pressure)
- Reduces risk of cardiovascular events such as stroke
- May be used in patients requiring combination therapy
Dosage:
Adults:
- One tablet once daily, preferably in the morning before meals
Dose should be individualized based on patient response and tolerability.
Side Effects:
Common:
- Dizziness
- Headache
- Dry cough (ACE inhibitor effect)
- Fatigue
Less common:
- Hypotension
- Electrolyte imbalance (low potassium or sodium)
- Nausea
Serious (rare):
- Angioedema (swelling of face, lips, throat)
- Kidney impairment
- Severe hypotension
Warnings & Precautions:
- Monitor blood pressure, renal function, and electrolytes regularly
- Use cautiously in patients with kidney disease or dehydration
- May cause persistent dry cough
- Risk of first-dose hypotension, especially in volume-depleted patients
- Avoid potassium supplements unless advised
Pregnancy & Lactation:
Pregnancy:
- Contraindicated (especially 2nd and 3rd trimester) – may cause fetal harm
Breastfeeding:
- Not recommended; consult doctor before use
Drug Interactions:
- Potassium-sparing diuretics / supplements – risk of hyperkalemia
- NSAIDs – reduced antihypertensive effect and risk of kidney damage
- Lithium – increased lithium toxicity
- Other antihypertensives – additive blood pressure lowering
- Diuretics – increased risk of hypotension
Contraindications:
- Hypersensitivity to ACE inhibitors or sulfonamides
- History of angioedema
- Severe renal impairment
- Pregnancy
- Concomitant use with aliskiren in diabetic patients
Price: Ksh 3,333.9/-
Notes:
Pack Size: 30s