Ceovit Tablets

Class: Vitamin C

Manufacturer: Square Pharmaceutical Ltd, Pabna Unit Salgaria, Pabna, Bangladesh

Dosage Form: Tablet

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Uses:

Ceovit is indicated for prevention and treatment of scurvy. It may be indicated in pregnancy, lactation, infection, trauma, burns, cold exposure, following surgery, fever, stress, peptic ulcer, cancer, methaemoglobinaemia and in infants receiving unfortified formulas. It is also prescribed for haematuria, dental caries, pyorrhea, acne, infertility, atherosclerosis, fractures, leg ulcers, hay fever, vascular thrombosis prevention, levodopa toxicity, succinyl-choline toxicity, arsenic toxicity e.t.c.

To reduce the risk of stroke in the elderly, long-term supplementation with ceovit is essential.

Dosage:

For the treatment of scurvy: 1-2 tablets daily; but dose may be increased depending on the severity of the condition.

For the reduction of risk of stroke in the elderly: 1-2 tablets daily.

In other cases: 1 tablet daily as directed by the physician.

Maximum safe dose is 2000mg daily in divided doses.

Side Effects:

Vitamin C has little toxicity and only mega-doses of vitamin C may cause diarrhea, abdominal bloating, iron over-absorption that is harmful in patients with thalassaemia, sideroblastic anemia, and haemochromatatosis; hyperoxaluria, hyperuricosuria, and hemolysis in patients with glucose-6 phosphate dehydrogenase deficiency. A pregnant woman taking more than 5g/day may suffer fetal abortion

Warnings & Precautions:

Vitamin C in mega-doses has been contraindicated for patients with hyperoxaluria.

Pregnancy & Lactation:

The drug is safe in normal doses in pregnant women, but a daily intake of 5gm or more is reported to have caused abortion. The drug may be taken safely during lactation.

Drug Interactions:

Potentially hazardous interactions:

Ascorbic acid is incompatible in solution with aminophylline, bleomycin, erythromycin, lactobionate, nafcillin, nitrofurantoin sodium, conjugated oestrogen, sodium bicarbonate, sulphafurazole diethanolamine, chloramphenicol sodium succinate, chlorthiazide sodium and hydrocortisone sodium succinate.

Useful interactions

Ascorbic acid increases the apparent half-life of paracetamol and enhance iron absorption from the gastrointestinal tract.

Contraindications:

Ingestion of megadose (more than 1000mg daily) of vitamin C during pregnancy has resulted in scurvy in neonates. Vitamin C itself is a reactive substance in the redox system and can give rise to false positive reactions in certain analytical tests for glucose, uric acid, creatine and occult blood.

Price: Ksh 2,000

Notes:

Ref: 2000005415

Pack size: 200s