Artorva Tablets

Atorvastatin 10 mg, 20 mg, 40 mg

Class: HMG-CoA Reductase Inhibitor (Statin) – Lipid-lowering agent

Manufacturer: Zydus Cadila

Dosage Form: Film-coated tablets

Similar Brands: Atorid (atorvastatin) and Lolip 20mg (artorvastatin)

Uses:

  • Hypercholesterolaemia

  • Mixed dyslipidaemia

  • Prevention of cardiovascular events (MI, stroke)

  • Secondary prevention in patients with established cardiovascular disease

  • Diabetic patients at high cardiovascular risk

Dosage:

Adults:

  • Usual starting dose: 10–20 mg once daily

  • High-risk patients: 40 mg once daily

  • Maximum dose: 80 mg daily

Can be taken any time of day, with or without food.
Dose adjustment based on lipid profile response.

Side Effects:

Common:

  • Headache

  • Nausea

  • Abdominal pain

  • Muscle aches (myalgia)

Less common:

  • Elevated liver enzymes

  • Muscle weakness

Rare but serious:

  • Myopathy

  • Rhabdomyolysis

  • Severe liver injury

Warnings & Precautions:

  • Check baseline liver function tests before initiation.

  • Monitor for unexplained muscle pain or weakness.

  • Use cautiously in patients with liver disease.

  • Avoid excessive alcohol intake.

  • Risk increases when combined with certain interacting drugs.

Pregnancy & Lactation:

Contraindicated in pregnancy (Category X).
Contraindicated during breastfeeding.

Drug Interactions:

  • Strong CYP3A4 inhibitors (e.g., clarithromycin, erythromycin)

  • Azole antifungals

  • Protease inhibitors

  • Cyclosporine

  • Fibrates (↑ risk of myopathy)

  • Grapefruit juice (↑ atorvastatin levels)

  • Warfarin (monitor INR)

Contraindications:

  • Active liver disease

  • Persistent unexplained elevation of transaminases

  • Pregnancy and breastfeeding

  • Hypersensitivity to atorvastatin

Price: Ksh 1200/- (Artorva Tablets 20mg)

Notes: