Salbutamol Sulphate (equivalent to Salbutamol 2 mg/5 mL), Bromhexine Hydrochloride 4 mg/5 mL, Guaifenesin 100 mg/5 mL, and Menthol 1 mg/5 mL
Class: Expectorant / Mucolytic + Bronchodilator cough syrup
Manufacturer: Sphinx Pharmaceuticals Limited
Dosage Form: Syrup
Similar Brands:
Uses:
Symptomatic relief of productive (wet/chesty) cough and associated conditions where mucus plugging, bronchospasm, and expectoration issues coexist, including:
- Cough with thick/viscid mucus from common cold, flu, or respiratory infections.
- Bronchitis (acute/chronic), bronchial asthma exacerbations, emphysema, or other bronchopulmonary disorders.
- Throat/lung/airway inflammation with congestion.
Helps loosen/thin mucus for easier coughing out, relieves bronchospasm, and improves breathing. Not for dry cough (may worsen); not curative for infections (use antibiotics if bacterial)—adjunctive for symptom relief.
Dosage:
Take orally (with or without food; often after meals to reduce GI upset). Use measuring device for accuracy. Typical (follow label/pharmacist/doctor advice):
Adults and adolescents >12 years: 10–20 mL (2–4 teaspoonfuls) 3 times daily.
Children 6–12 years: 10 mL (2 teaspoonfuls) 3 times daily.
Children under 6 years: 5–10 mL 3 times daily (consult doctor/pharmacist; often not recommended without guidance).
Duration: Short-term (e.g., 4–5 days); seek medical advice if no improvement or symptoms worsen (e.g., fever, wheezing, shortness of breath). Not for infants <2 years without specialist advice.
Adults and adolescents >12 years: 10–20 mL (2–4 teaspoonfuls) 3 times daily.
Children 6–12 years: 10 mL (2 teaspoonfuls) 3 times daily.
Children under 6 years: 5–10 mL 3 times daily (consult doctor/pharmacist; often not recommended without guidance).
Duration: Short-term (e.g., 4–5 days); seek medical advice if no improvement or symptoms worsen (e.g., fever, wheezing, shortness of breath). Not for infants <2 years without specialist advice.
Side Effects:
Common (mild/transient): Nausea, vomiting, diarrhea, abdominal pain/upset, headache, dizziness, tremor (especially hands from salbutamol), palpitations/tachycardia, muscle cramps, restlessness, dry mouth/throat.
Less common: Rash, itching, sweating, taste changes, increased heart rate.
Serious (rare, seek immediate care): Severe allergic reactions (angioedema, urticaria, breathing difficulty), worsening bronchospasm, severe hypokalemia (low potassium—muscle weakness/irregular heartbeat), or signs of overdose (extreme tremors, rapid heartbeat).
Less common: Rash, itching, sweating, taste changes, increased heart rate.
Serious (rare, seek immediate care): Severe allergic reactions (angioedema, urticaria, breathing difficulty), worsening bronchospasm, severe hypokalemia (low potassium—muscle weakness/irregular heartbeat), or signs of overdose (extreme tremors, rapid heartbeat).
Warnings & Precautions:
Use caution in asthma (monitor for paradoxic worsening), cardiovascular disorders (hypertension, arrhythmias—salbutamol may increase heart rate), diabetes (may affect blood sugar), hyperthyroidism, or peptic ulcer history.
Not for dry cough or if no mucus present.
Seek doctor if persistent cough >4–5 days, high fever, chest pain, bloody sputum, or breathing difficulty.
Contains excipients (e.g., sucrose—caution in diabetes; parabens—possible allergy).
Avoid alcohol (enhances dizziness/sedation).
Not for dry cough or if no mucus present.
Seek doctor if persistent cough >4–5 days, high fever, chest pain, bloody sputum, or breathing difficulty.
Contains excipients (e.g., sucrose—caution in diabetes; parabens—possible allergy).
Avoid alcohol (enhances dizziness/sedation).
Pregnancy & Lactation:
Pregnancy: Limited data; salbutamol/bromhexine/guaifenesin often used if needed but consult doctor (potential risks—avoid unless benefit outweighs).
Lactation: Guaifenesin excreted in small amounts in milk; limited data on others—consult provider (monitor infant for GI effects or restlessness).
Lactation: Guaifenesin excreted in small amounts in milk; limited data on others—consult provider (monitor infant for GI effects or restlessness).
Drug Interactions:
Beta-blockers: May counteract salbutamol’s bronchodilator effect.
Other sympathomimetics: Additive tachycardia/tremors.
MAO inhibitors/antidepressants: Potential interactions.
Diuretics/steroids/xanthines: May potentiate hypokalemia.
Other sympathomimetics: Additive tachycardia/tremors.
MAO inhibitors/antidepressants: Potential interactions.
Diuretics/steroids/xanthines: May potentiate hypokalemia.
Contraindications:
Known hypersensitivity to salbutamol, bromhexine, guaifenesin, menthol, or excipients.
Severe cardiovascular disease (e.g., uncontrolled arrhythmias, ischemic heart disease).
Children under 2–6 years (per some labels—consult).
Untreated hyperthyroidism or conditions worsened by beta-agonists.
Severe cardiovascular disease (e.g., uncontrolled arrhythmias, ischemic heart disease).
Children under 2–6 years (per some labels—consult).
Untreated hyperthyroidism or conditions worsened by beta-agonists.
Price: Ksh 150/- (Ascoff Expectorant 100ml), 100/- (Ascoff Expectorant 60ml)
Notes:
Pack Size: 60mls, 100ml