Probeta N Drops

Class: Eye, Ear and Nose Preparation

Manufacturer: The House of Quality Pharmaceuticals, ATCO LABORATORIES LIMITED B-18, S.I.T.E, KARACHI-PAKISTAN

Dosage Form: Drops (7.5ml in plastic dropper bottle)

Similar Brands:

Uses:

Eye: Non infected steroid responsive inflammatory conditions e.g. uveitis, marginal keratitis, allergic conjunctivitis, Blepharitis, Episcleritis, where prophylaxis against secondary bacterial infection is desired.

Ear: Otitis externa and other steroid responsive inflammatory conditions where bacterial infection is present or suspected.

Nose: Steroid responsive inflammatory conditions where infection is present or suspected.

Dosage:

For external use only

Eye: 1 or 2 drops instilled into the eye every one or two hours until signs of improvement are apparent, when the frequency may be reduced.

Ear: 2 to 3 drops instilled into the ear every two or three hours until signs or improvement are apparent, when the frequency can be reduced

Nose: 2 or 3 drops instilled into each nostril two or three times daily.

Side Effects:

Eye drops containing corticosteroids cause a serious rise in intra-occular pressure in small percentage of the population, including most of those with a family history of glaucoma. A milder rise may be experienced by a larger proportion of subjects if treatment is continued for longer than two weeks.

Thinning of the cornea leading to perforation has occurred with use of topical corticosteroids.

Acute sensitization of Neomycin Sulphate is rare event.

Cataract is reported to have occurred after unduly prolonged treatment of eye conditions with topical corticosteroids.

Excessive and prolonged intranasal usage above the recommended dose may include systemic side effects.

Warnings & Precautions:

Steroids should not be administered to “red eyes” until a definitive diagnosis is made. Treatment with steroid preparations should not be repeated or prolonged without regular review ot exclude raised intra-ocular pressure or unsuspected infections.

Pregnancy & Lactation:

Topical administration of corticosteroids to pregnant animals can cause abnormalities of foetal development. The relevance of this finding to human beings has not been established; however, topical steroids should not be used extensively in pregnancy i.e. in large amounts or for prolong periods

Drug Interactions:

The unnecessary topical use of Neomycin Sulphate containing products should be avoided in order to minimize occurrence of neomycin resistant organisms (and organisms cross-resistant to other aminoglycosides).

Contraindications:

Bacterial, viral, fungal, tuberculosis or purulent conditions.

Use in the eye is contraindicated if glaucoma is present or where herpatic keratitis (e.g dentritic ulcer) is considered a possibility.

Inadvertent use of topical steroids in the latter condition can lead to extension of the ulcer and marked visual deterioration.

Hypersensitivity to the preparation

Because of the risk of ototoxicity, preparation containing Neomycin Sulphate should not be used until an intact tympanic membrane has been visualized

Price: Ksh 150

Notes:

Available in most pharmacies in Kenya